产品货号：
Z37440
中文名称：
人CD22抗体
英文名称：
Anti-human CD22 Antibody(Clone#MYG13)
产品规格：
100μg|500μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-human CD22 Antibody Unconjugated,Flow Validated (Clone#MYG13) |
| 指标别名 | B cell receptor CD22;BL CAM;CD22;CD22 molecule;SIGLEC 2;SIGLEC2;T cell surface antigen Leu 14 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM |
| 基因名称 | CD22 |
| 克隆号 | MYG13 |
| 抗体来源 | Mouse |
| 计算分子量 | 95kDa |
| 成分 | PBS with 0.09% NaN3 |
| 纯化方式 | Protein A purified |
| 浓度 | 0.5～1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure. |
| 产品形态 | 溶液 |
| 保存条件 | Store at 4℃ for one year.Do not freeze. |
| 背景资料 | CD22 or cluster of differentiation-22,is a molecule belonging to the SIGLEC family of lectins.This gene is mapped to 19q13.2.It is found on the surface of mature B cells and to a lesser extent on some immature B cells.Generally speaking,CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.It is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering.CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.This gene can downmodulate signaling through the IgM and IgD B-cell receptors (BCRs),but not through the IgG BCR,because the IgG cytoplasmic tail prevents CD22 phosphorylation and actually enhances IgG-BCR signaling. |
| Uniprot ID | P20273 |
| 基因名全称 | B-cell receptor CD22 |
| 蛋白名全称 | B-cell receptor CD22 |
| 推荐稀释比 | User need to optimize the dilution ratio for this antibody |
相关搜索：人CD22抗体，human CD22单抗，Anti-human CD22 Antibody(Clone#MYG13)